Cargando…

High-Fat Diet Aggravates the Intestinal Barrier Injury via TLR4-RIP3 Pathway in a Rat Model of Severe Acute Pancreatitis

OBJECTIVE: For patients with severe acute pancreatitis (SAP), a high body mass index (BMI) increases the possibility of infection derived from the intestine. In this study, we evaluate whether TAK242 can alleviate severe acute pancreatitis-associated injury of intestinal barrier in high-fat diet-fed...

Descripción completa

Detalles Bibliográficos
Autores principales:	Su, Ying-ru, Hong, Yu-pu, Mei, Fang-chao, Wang, Chen-yang, Li, Man, Zhou, Yu, Zhao, Kai-liang, Yu, Jia, Wang, Wei-xing
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2019
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6942875/ https://www.ncbi.nlm.nih.gov/pubmed/31933540 http://dx.doi.org/10.1155/2019/2512687

Ejemplares similares

High-Fat Diet Aggravates Acute Pancreatitis via TLR4-Mediated Necroptosis and Inflammation in Rats
por: Hong, Yu-pu, et al.
Publicado: (2020)

Paneth Cell Ablation Aggravates Pancreatic and Intestinal Injuries in a Rat Model of Acute Necrotizing Pancreatitis after Normal and High-Fat Diet
por: Guo, Yuecheng, et al.
Publicado: (2019)

Hepatic Nampt Deficiency Aggravates Dyslipidemia and Fatty Liver in High Fat Diet Fed Mice
por: Wang, Dao-Xin, et al.
Publicado: (2023)

High‐fat diet aggravates the severity of the in vitro posttraumatic osteoarthritis model through macrophagic FBW7
por: Duan, Lijun, et al.
Publicado: (2023)

Obesity Aggravates Acute Pancreatitis via Damaging Intestinal Mucosal Barrier and Changing Microbiota Composition in Rats
por: Ye, Cheng, et al.
Publicado: (2019)

Dysbiosis of intestinal microbiota in early life aggravates high-fat diet induced dysmetabolism in adult mice
por: Miao, Z. H., et al.
Publicado: (2021)

Nonylphenol aggravates non-alcoholic fatty liver disease in high sucrose-high fat diet-treated rats
por: Yu, Jie, et al.
Publicado: (2018)

Sanguinarine Improves Intestinal Health in Grass Carp Fed High-Fat Diets: Involvement of Antioxidant, Physical and Immune Barrier, and Intestinal Microbiota
por: Shi, Yong, et al.
Publicado: (2023)

High-fat diet aggravates postoperative cognitive dysfunction in aged mice
por: Wei, Lan, et al.
Publicado: (2018)

Up-Regulation of RIP3 Alleviates Prostate Cancer Progression by Activation of RIP3/MLKL Signaling Pathway and Induction of Necroptosis
por: Wang, Ke-jie, et al.
Publicado: (2020)

Chronic constant light exposure aggravates high fat diet-induced renal injury in rats
por: Xing, Lin, et al.
Publicado: (2022)

Impact of a high-fat diet on intestinal stem cells and epithelial barrier function in middle-aged female mice
por: Xie, Yu, et al.
Publicado: (2020)

Activated Drp1 regulates p62-mediated autophagic flux and aggravates inflammation in cerebral ischemia-reperfusion via the ROS-RIP1/RIP3-exosome axis
por: Zeng, Xue, et al.
Publicado: (2022)

Ameliorating Effects of TRIM67 against Intestinal Inflammation and Barrier Dysfunction Induced by High Fat Diet in Obese Mice
por: Luo, Qihui, et al.
Publicado: (2022)

High Fat High Cholesterol Diet (Western Diet) Aggravates Atherosclerosis, Hyperglycemia and Renal Failure in Nephrectomized LDL Receptor Knockout Mice: Role of Intestine Derived Lipopolysaccharide
por: Ghosh, Siddhartha S., et al.
Publicado: (2015)

RIP Links TLR4 to Akt and Is Essential for Cell Survival in Response to LPS Stimulation
por: Vivarelli, Marina S., et al.
Publicado: (2004)

TLR3/TICAM-1 signaling in tumor cell RIP3-dependent necroptosis
por: Seya, Tsukasa, et al.
Publicado: (2012)

Bilophila wadsworthia aggravates high fat diet induced metabolic dysfunctions in mice
por: Natividad, Jane M., et al.
Publicado: (2018)

Tim-1 Deficiency Aggravates High-Fat Diet-Induced Steatohepatitis in Mice
por: George, Jasmine, et al.
Publicado: (2021)

Dapagliflozin Alleviates Renal Fibrosis by Inhibiting RIP1-RIP3-MLKL-Mediated Necroinflammation in Unilateral Ureteral Obstruction
por: Xuan, Mei Ying, et al.
Publicado: (2022)

The Mechanism of Lipopolysaccharide Escaping the Intestinal Barrier in Megalobrama amblycephala Fed a High-Fat Diet
por: Dai, Yong-Jun, et al.
Publicado: (2022)

RIP3-mediated necroptosis is regulated by inter-filament assembly of RIP homotypic interaction motif
por: Hu, Hong, et al.
Publicado: (2020)

Chronic unpredictable mild stress combined with a high-fat diets aggravates atherosclerosis in rats
por: Wang, Shuling, et al.
Publicado: (2014)

Reducing RIP140 Expression in Macrophage Alters ATM Infiltration, Facilitates White Adipose Tissue Browning, and Prevents High-Fat Diet–Induced Insulin Resistance
por: Liu, Pu-Ste, et al.
Publicado: (2014)

Regulation of intestinal homeostasis and tumorigenesis by the transcriptional coregulator RIP140
por: Cavaillès, Vincent, et al.
Publicado: (2014)

Alteration and the Function of Intestinal Microbiota in High-Fat-Diet- or Genetics-Induced Lipid Accumulation
por: Qiao, Fang, et al.
Publicado: (2021)

Necrostatin-1 Ameliorates Peripheral Nerve Injury-Induced Neuropathic Pain by Inhibiting the RIP1/RIP3 Pathway
por: Liang, Ying-Xia, et al.
Publicado: (2019)

Morphine Induces Bacterial Translocation in Mice by Compromising Intestinal Barrier Function in a TLR-Dependent Manner
por: Meng, Jingjing, et al.
Publicado: (2013)

Increased synovial lipodystrophy induced by high fat diet aggravates synovitis in experimental osteoarthritis
por: Larrañaga-Vera, Ane, et al.
Publicado: (2017)

MeRIP-PF: An Easy-to-use Pipeline for High-resolution Peak-finding in MeRIP-Seq Data
por: Li, Yuli, et al.
Publicado: (2013)

miR-30 Promotes Thermogenesis and the Development of Beige Fat by Targeting RIP140
por: Hu, Fang, et al.
Publicado: (2015)

RIP3 knockdown inhibits necroptosis of human intestinal epithelial cells via TLR4/MyD88/NF-κB signaling and ameliorates murine colitis
por: Duan, Chaoqin, et al.
Publicado: (2022)

IL-10 Deficiency Aggravates Renal Inflammation, Fibrosis and Functional Failure in High-Fat Dieted Obese Mice
por: Kim, Dae Hwan, et al.
Publicado: (2021)

Obesogenic diet-induced gut barrier dysfunction and pathobiont expansion aggravate experimental colitis
por: Lee, June-Chul, et al.
Publicado: (2017)

Toll-like receptors TLR2 and TLR4 block the replication of pancreatic β cells in diet-induced obesity
por: Ji, Yewei, et al.
Publicado: (2019)

Mechanism of RIP2 enhancing stemness of glioma cells induces temozolomide resistance
por: Wang, Xiao‐liang, et al.
Publicado: (2022)

Maternal Low-Protein Diet during Puberty and Adulthood Aggravates Lipid Metabolism of Their Offspring Fed a High-Fat Diet in Mice
por: Huang, Xiaohua, et al.
Publicado: (2022)

CTRP1 Aggravates Cardiac Dysfunction Post Myocardial Infarction by Modulating TLR4 in Macrophages
por: Gu, Yang, et al.
Publicado: (2021)

(-)-Epicatechin protects the intestinal barrier from high fat diet-induced permeabilization: Implications for steatosis and insulin resistance
por: Cremonini, Eleonora, et al.
Publicado: (2017)

Isocitrate dehydrogenase 2 deficiency aggravates prolonged high-fat diet intake-induced hypertension
por: Noh, Mi Ra, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_v3btmsl5jj70vu9qm0ook4uill