PRMT1-mediated methylation of the microprocessor-associated proteins regulates microRNA biogenesis

MicroRNA (miRNA) biogenesis is a tightly controlled multi-step process operated in the nucleus by the activity of the Microprocessor and its associated proteins. Through high resolution mass spectrometry (MS)- proteomics we discovered that this complex is extensively methylated, with 84 methylated s...

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Detalles Bibliográficos
Autores principales: Spadotto, Valeria, Giambruno, Roberto, Massignani, Enrico, Mihailovich, Marija, Maniaci, Marianna, Patuzzo, Francesca, Ghini, Francesco, Nicassio, Francesco, Bonaldi, Tiziana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Data Resources and Analyses
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6943135/
https://www.ncbi.nlm.nih.gov/pubmed/31777917
http://dx.doi.org/10.1093/nar/gkz1051

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6943135/
https://www.ncbi.nlm.nih.gov/pubmed/31777917
http://dx.doi.org/10.1093/nar/gkz1051

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