Acute Colchicine Poisoning Causes Endotoxemia via the Destruction of Intestinal Barrier Function: The Curative Effect of Endotoxin Prevention in a Murine Model

BACKGROUND: Colchicine binds to intracellular tubulin and prevents mitosis. Colchicine is also used as an anti-inflammatory drug. Meanwhile, excess administration of medication or accidental ingestion of colchicine-containing plants can cause acute colchicine poisoning, which initially results in ga...

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Detalles Bibliográficos
Autores principales: Horioka, Kie, Tanaka, Hiroki, Isozaki, Shotaro, Konishi, Hiroaki, Fujiya, Mikihiro, Okuda, Katsuhiro, Asari, Masaru, Shiono, Hiroshi, Ogawa, Katsuhiro, Shimizu, Keiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2019
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Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6943411/
https://www.ncbi.nlm.nih.gov/pubmed/31312993
http://dx.doi.org/10.1007/s10620-019-05729-w

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