CX-5461 Inhibits Pancreatic Ductal Adenocarcinoma Cell Growth, Migration and Induces DNA Damage

Background: Inhibition of ribosome biogenesis has recently emerged as a promising strategy for the treatment of metastatic tumors. The RNA polymerase I inhibitor CX-5461 has shown efficacy in a panel of cancer types and is currently being tested in clinical trials. However, further preclinical studi...

Descripción completa

Detalles Bibliográficos
Autores principales: El Hassouni, Btissame, Mantini, Giulia, Immordino, Benoît, Peters, Godefridus J., Giovannetti, Elisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6943431/
https://www.ncbi.nlm.nih.gov/pubmed/31817270
http://dx.doi.org/10.3390/molecules24244445

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6943431/
https://www.ncbi.nlm.nih.gov/pubmed/31817270
http://dx.doi.org/10.3390/molecules24244445

Ejemplares similares