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CX-5461 Inhibits Pancreatic Ductal Adenocarcinoma Cell Growth, Migration and Induces DNA Damage

Background: Inhibition of ribosome biogenesis has recently emerged as a promising strategy for the treatment of metastatic tumors. The RNA polymerase I inhibitor CX-5461 has shown efficacy in a panel of cancer types and is currently being tested in clinical trials. However, further preclinical studi...

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Detalles Bibliográficos
Autores principales:	El Hassouni, Btissame, Mantini, Giulia, Immordino, Benoît, Peters, Godefridus J., Giovannetti, Elisa
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6943431/ https://www.ncbi.nlm.nih.gov/pubmed/31817270 http://dx.doi.org/10.3390/molecules24244445

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