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Rational Drug Design of Peptide-Based Therapies for Sickle Cell Disease

Sickle cell disease (SCD) is a group of inherited disorders affecting red blood cells, which is caused by a single mutation that results in substitution of the amino acid valine for glutamic acid in the sixth position of the β-globin chain of hemoglobin. These mutant hemoglobin molecules, called hem...

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Detalles Bibliográficos
Autores principales: Olubiyi, Olujide O., Olagunju, Maryam O., Strodel, Birgit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6943517/
https://www.ncbi.nlm.nih.gov/pubmed/31842406
http://dx.doi.org/10.3390/molecules24244551