Common Secondary and Tertiary Structural Features of Aptamer–Ligand Interaction Shared by RNA Aptamers with Different Primary Sequences

Aptamer selection can yield many oligonucleotides with different sequences and affinities for the target molecule. Here, we have combined computational and experimental approaches to understand if aptamers with different sequences but the same molecular target share structural and dynamical features...

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Detalles Bibliográficos
Autores principales: Ilgu, Muslum, Yan, Shuting, Khounlo, Ryan M., Lamm, Monica H., Nilsen-Hamilton, Marit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6943582/
https://www.ncbi.nlm.nih.gov/pubmed/31835789
http://dx.doi.org/10.3390/molecules24244535

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6943582/
https://www.ncbi.nlm.nih.gov/pubmed/31835789
http://dx.doi.org/10.3390/molecules24244535

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