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The Potential Use of Resveratrol for Cancer Prevention
In addition to the traditional treatments of cancer and cancer prevention, the use of natural compounds, especially those found in food, should be considered. To clarify if resveratrol has the potential for cancer prevention and the possibility of use in therapy, the following must be taken into acc...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6943596/ https://www.ncbi.nlm.nih.gov/pubmed/31835371 http://dx.doi.org/10.3390/molecules24244506 |
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author | Vervandier-Fasseur, Dominique Latruffe, Norbert |
author_facet | Vervandier-Fasseur, Dominique Latruffe, Norbert |
author_sort | Vervandier-Fasseur, Dominique |
collection | PubMed |
description | In addition to the traditional treatments of cancer and cancer prevention, the use of natural compounds, especially those found in food, should be considered. To clarify if resveratrol has the potential for cancer prevention and the possibility of use in therapy, the following must be taken into account: data from epidemiology, clinical protocol (case and control), preclinical studies (lab animals), use of established cell lines as models of cancer cells, test tube assays (enzymes activities), and requirements of nanotechnologies in order to discover new drugs to fight cancer. From this perspective and future expected advances, more information is needed such as improved efficacy, methods of application, and the synergistic sensitization of resveratrol as an adjuvant. In addition, resveratrol nanoformulation is considered to overcome its weak bioavailability. |
format | Online Article Text |
id | pubmed-6943596 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-69435962020-01-10 The Potential Use of Resveratrol for Cancer Prevention Vervandier-Fasseur, Dominique Latruffe, Norbert Molecules Review In addition to the traditional treatments of cancer and cancer prevention, the use of natural compounds, especially those found in food, should be considered. To clarify if resveratrol has the potential for cancer prevention and the possibility of use in therapy, the following must be taken into account: data from epidemiology, clinical protocol (case and control), preclinical studies (lab animals), use of established cell lines as models of cancer cells, test tube assays (enzymes activities), and requirements of nanotechnologies in order to discover new drugs to fight cancer. From this perspective and future expected advances, more information is needed such as improved efficacy, methods of application, and the synergistic sensitization of resveratrol as an adjuvant. In addition, resveratrol nanoformulation is considered to overcome its weak bioavailability. MDPI 2019-12-09 /pmc/articles/PMC6943596/ /pubmed/31835371 http://dx.doi.org/10.3390/molecules24244506 Text en © 2019 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Vervandier-Fasseur, Dominique Latruffe, Norbert The Potential Use of Resveratrol for Cancer Prevention |
title | The Potential Use of Resveratrol for Cancer Prevention |
title_full | The Potential Use of Resveratrol for Cancer Prevention |
title_fullStr | The Potential Use of Resveratrol for Cancer Prevention |
title_full_unstemmed | The Potential Use of Resveratrol for Cancer Prevention |
title_short | The Potential Use of Resveratrol for Cancer Prevention |
title_sort | potential use of resveratrol for cancer prevention |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6943596/ https://www.ncbi.nlm.nih.gov/pubmed/31835371 http://dx.doi.org/10.3390/molecules24244506 |
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