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The Potential Use of Resveratrol for Cancer Prevention

In addition to the traditional treatments of cancer and cancer prevention, the use of natural compounds, especially those found in food, should be considered. To clarify if resveratrol has the potential for cancer prevention and the possibility of use in therapy, the following must be taken into acc...

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Detalles Bibliográficos
Autores principales: Vervandier-Fasseur, Dominique, Latruffe, Norbert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6943596/
https://www.ncbi.nlm.nih.gov/pubmed/31835371
http://dx.doi.org/10.3390/molecules24244506
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author Vervandier-Fasseur, Dominique
Latruffe, Norbert
author_facet Vervandier-Fasseur, Dominique
Latruffe, Norbert
author_sort Vervandier-Fasseur, Dominique
collection PubMed
description In addition to the traditional treatments of cancer and cancer prevention, the use of natural compounds, especially those found in food, should be considered. To clarify if resveratrol has the potential for cancer prevention and the possibility of use in therapy, the following must be taken into account: data from epidemiology, clinical protocol (case and control), preclinical studies (lab animals), use of established cell lines as models of cancer cells, test tube assays (enzymes activities), and requirements of nanotechnologies in order to discover new drugs to fight cancer. From this perspective and future expected advances, more information is needed such as improved efficacy, methods of application, and the synergistic sensitization of resveratrol as an adjuvant. In addition, resveratrol nanoformulation is considered to overcome its weak bioavailability.
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spelling pubmed-69435962020-01-10 The Potential Use of Resveratrol for Cancer Prevention Vervandier-Fasseur, Dominique Latruffe, Norbert Molecules Review In addition to the traditional treatments of cancer and cancer prevention, the use of natural compounds, especially those found in food, should be considered. To clarify if resveratrol has the potential for cancer prevention and the possibility of use in therapy, the following must be taken into account: data from epidemiology, clinical protocol (case and control), preclinical studies (lab animals), use of established cell lines as models of cancer cells, test tube assays (enzymes activities), and requirements of nanotechnologies in order to discover new drugs to fight cancer. From this perspective and future expected advances, more information is needed such as improved efficacy, methods of application, and the synergistic sensitization of resveratrol as an adjuvant. In addition, resveratrol nanoformulation is considered to overcome its weak bioavailability. MDPI 2019-12-09 /pmc/articles/PMC6943596/ /pubmed/31835371 http://dx.doi.org/10.3390/molecules24244506 Text en © 2019 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Vervandier-Fasseur, Dominique
Latruffe, Norbert
The Potential Use of Resveratrol for Cancer Prevention
title The Potential Use of Resveratrol for Cancer Prevention
title_full The Potential Use of Resveratrol for Cancer Prevention
title_fullStr The Potential Use of Resveratrol for Cancer Prevention
title_full_unstemmed The Potential Use of Resveratrol for Cancer Prevention
title_short The Potential Use of Resveratrol for Cancer Prevention
title_sort potential use of resveratrol for cancer prevention
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6943596/
https://www.ncbi.nlm.nih.gov/pubmed/31835371
http://dx.doi.org/10.3390/molecules24244506
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