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Senescent Stem and Transient Amplifying Cells in Crohn’s Disease Intestine

We demonstrate presence of senescent (p16(+), p21(+)) epithelial cells in the stem and transient amplifying cell niches of the intestine in Crohn’s disease. This may explain why Crohn’s lesions recur in the same places.

Detalles Bibliográficos
Autores principales:	Wang, Xiaoyan, Bootsma, Hendrika, Kroese, Frans, Dijkstra, Gerard, Pringle, Sarah
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2020
Materias:	Letters to the Editor
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6943680/ https://www.ncbi.nlm.nih.gov/pubmed/31769481 http://dx.doi.org/10.1093/ibd/izz295

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