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δ-secretase in neurodegenerative diseases: mechanisms, regulators and therapeutic opportunities
Mammalian asparagine endopeptidase (AEP) is a cysteine protease that cleaves its protein substrates on the C-terminal side of asparagine residues. Converging lines of evidence indicate that AEP may be involved in the pathogenesis of several neurological diseases, including Alzheimer’s disease, Parki...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6943888/ https://www.ncbi.nlm.nih.gov/pubmed/31911834 http://dx.doi.org/10.1186/s40035-019-0179-3 |