Soybean lecithin stabilizes disulfiram nanosuspensions with a high drug-loading content: remarkably improved antitumor efficacy

Disulfiram (DSF) has been considered as “Repurposing drug” in cancer therapy in recent years based on its good antitumor efficacy. DSF is traditionally used as an oral drug in the treatment of alcoholism. To overcome its rapid degradation and instability, DSF nanosuspensions (DSF/SPC-NSps) were prep...

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Detalles Bibliográficos
Autores principales: Li, Haowen, Liu, Biao, Ao, Hui, Fu, Jingxin, Wang, Yian, Feng, Yue, Guo, Yifei, Wang, Xiangtao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6943900/
https://www.ncbi.nlm.nih.gov/pubmed/31907045
http://dx.doi.org/10.1186/s12951-019-0565-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6943900/
https://www.ncbi.nlm.nih.gov/pubmed/31907045
http://dx.doi.org/10.1186/s12951-019-0565-0

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