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Two isostructural 3-(5-ar­yloxy-3-methyl-1-phenyl-1H-pyrazol-4-yl)-1-(thio­phen-2-yl)prop-2-en-1-ones: disorder and supra­molecular assembly

Two new chalcones containing both pyrazole and thio­phene substituents have been prepared and structurally characterized. 3-(3-Methyl-5-phen­oxy-1-phenyl-1H-pyrazol-4-yl)-1-(thio­phen-2-yl)prop-2-en-1-one, C(23)H(18)N(2)O(2)S (I), and 3-[3-methyl-5-(2-methyl­phen­oxy)-1-phenyl-1H-pyrazol-4-yl]-1-(th...

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Detalles Bibliográficos
Autores principales: Shaibah, Mohammed A. E., Yathirajan, Hemmige S., Manju, Nagaraj, Kalluraya, Balakrishna, Rathore, Ravindranath S., Glidewell, Christopher
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6944090/
https://www.ncbi.nlm.nih.gov/pubmed/31921451
http://dx.doi.org/10.1107/S205698901901658X
Descripción
Sumario:Two new chalcones containing both pyrazole and thio­phene substituents have been prepared and structurally characterized. 3-(3-Methyl-5-phen­oxy-1-phenyl-1H-pyrazol-4-yl)-1-(thio­phen-2-yl)prop-2-en-1-one, C(23)H(18)N(2)O(2)S (I), and 3-[3-methyl-5-(2-methyl­phen­oxy)-1-phenyl-1H-pyrazol-4-yl]-1-(thio­phen-2-yl)prop-2-en-1-one, C(24)H(20)N(2)O(2)S (II), are isomorphous as well as isostructural, and in each the thio­phene substituent is disordered over two sets of atomic sites having occupancies 0.844 (3) and 0.156 (3) in (I), and 0.883 (2) and 0.117 (2) in (II). In each structure, the mol­ecules are linked into sheets by a combination of C—H⋯N and C—H⋯O hydrogen bonds. Comparisons are made with some related compounds.