Two isostructural 3-(5-ar­yloxy-3-methyl-1-phenyl-1H-pyrazol-4-yl)-1-(thio­phen-2-yl)prop-2-en-1-ones: disorder and supra­molecular assembly

Two new chalcones containing both pyrazole and thio­phene substituents have been prepared and structurally characterized. 3-(3-Methyl-5-phen­oxy-1-phenyl-1H-pyrazol-4-yl)-1-(thio­phen-2-yl)prop-2-en-1-one, C(23)H(18)N(2)O(2)S (I), and 3-[3-methyl-5-(2-methyl­phen­oxy)-1-phenyl-1H-pyrazol-4-yl]-1-(th...

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Autores principales: Shaibah, Mohammed A. E., Yathirajan, Hemmige S., Manju, Nagaraj, Kalluraya, Balakrishna, Rathore, Ravindranath S., Glidewell, Christopher
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2020
Materias:
Research Communications
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6944090/
https://www.ncbi.nlm.nih.gov/pubmed/31921451
http://dx.doi.org/10.1107/S205698901901658X
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author Shaibah, Mohammed A. E.
Yathirajan, Hemmige S.
Manju, Nagaraj
Kalluraya, Balakrishna
Rathore, Ravindranath S.
Glidewell, Christopher
author_facet Shaibah, Mohammed A. E.
Yathirajan, Hemmige S.
Manju, Nagaraj
Kalluraya, Balakrishna
Rathore, Ravindranath S.
Glidewell, Christopher
author_sort Shaibah, Mohammed A. E.
collection PubMed
description Two new chalcones containing both pyrazole and thio­phene substituents have been prepared and structurally characterized. 3-(3-Methyl-5-phen­oxy-1-phenyl-1H-pyrazol-4-yl)-1-(thio­phen-2-yl)prop-2-en-1-one, C(23)H(18)N(2)O(2)S (I), and 3-[3-methyl-5-(2-methyl­phen­oxy)-1-phenyl-1H-pyrazol-4-yl]-1-(thio­phen-2-yl)prop-2-en-1-one, C(24)H(20)N(2)O(2)S (II), are isomorphous as well as isostructural, and in each the thio­phene substituent is disordered over two sets of atomic sites having occupancies 0.844 (3) and 0.156 (3) in (I), and 0.883 (2) and 0.117 (2) in (II). In each structure, the mol­ecules are linked into sheets by a combination of C—H⋯N and C—H⋯O hydrogen bonds. Comparisons are made with some related compounds.
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spelling pubmed-69440902020-01-09 Two isostructural 3-(5-ar­yloxy-3-methyl-1-phenyl-1H-pyrazol-4-yl)-1-(thio­phen-2-yl)prop-2-en-1-ones: disorder and supra­molecular assembly Shaibah, Mohammed A. E. Yathirajan, Hemmige S. Manju, Nagaraj Kalluraya, Balakrishna Rathore, Ravindranath S. Glidewell, Christopher Acta Crystallogr E Crystallogr Commun Research Communications Two new chalcones containing both pyrazole and thio­phene substituents have been prepared and structurally characterized. 3-(3-Methyl-5-phen­oxy-1-phenyl-1H-pyrazol-4-yl)-1-(thio­phen-2-yl)prop-2-en-1-one, C(23)H(18)N(2)O(2)S (I), and 3-[3-methyl-5-(2-methyl­phen­oxy)-1-phenyl-1H-pyrazol-4-yl]-1-(thio­phen-2-yl)prop-2-en-1-one, C(24)H(20)N(2)O(2)S (II), are isomorphous as well as isostructural, and in each the thio­phene substituent is disordered over two sets of atomic sites having occupancies 0.844 (3) and 0.156 (3) in (I), and 0.883 (2) and 0.117 (2) in (II). In each structure, the mol­ecules are linked into sheets by a combination of C—H⋯N and C—H⋯O hydrogen bonds. Comparisons are made with some related compounds. International Union of Crystallography 2020-01-01 /pmc/articles/PMC6944090/ /pubmed/31921451 http://dx.doi.org/10.1107/S205698901901658X Text en © Shaibah et al. 2020 http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution (CC-BY) Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited.http://creativecommons.org/licenses/by/4.0/
spellingShingle Research Communications
Shaibah, Mohammed A. E.
Yathirajan, Hemmige S.
Manju, Nagaraj
Kalluraya, Balakrishna
Rathore, Ravindranath S.
Glidewell, Christopher
Two isostructural 3-(5-ar­yloxy-3-methyl-1-phenyl-1H-pyrazol-4-yl)-1-(thio­phen-2-yl)prop-2-en-1-ones: disorder and supra­molecular assembly
title Two isostructural 3-(5-ar­yloxy-3-methyl-1-phenyl-1H-pyrazol-4-yl)-1-(thio­phen-2-yl)prop-2-en-1-ones: disorder and supra­molecular assembly
title_full Two isostructural 3-(5-ar­yloxy-3-methyl-1-phenyl-1H-pyrazol-4-yl)-1-(thio­phen-2-yl)prop-2-en-1-ones: disorder and supra­molecular assembly
title_fullStr Two isostructural 3-(5-ar­yloxy-3-methyl-1-phenyl-1H-pyrazol-4-yl)-1-(thio­phen-2-yl)prop-2-en-1-ones: disorder and supra­molecular assembly
title_full_unstemmed Two isostructural 3-(5-ar­yloxy-3-methyl-1-phenyl-1H-pyrazol-4-yl)-1-(thio­phen-2-yl)prop-2-en-1-ones: disorder and supra­molecular assembly
title_short Two isostructural 3-(5-ar­yloxy-3-methyl-1-phenyl-1H-pyrazol-4-yl)-1-(thio­phen-2-yl)prop-2-en-1-ones: disorder and supra­molecular assembly
title_sort two isostructural 3-(5-ar­yloxy-3-methyl-1-phenyl-1h-pyrazol-4-yl)-1-(thio­phen-2-yl)prop-2-en-1-ones: disorder and supra­molecular assembly
topic Research Communications
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6944090/
https://www.ncbi.nlm.nih.gov/pubmed/31921451
http://dx.doi.org/10.1107/S205698901901658X
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