Gabexate mesilate ameliorates the neuropathic pain in a rat model by inhibition of proinflammatory cytokines and nitric oxide pathway via suppression of nuclear factor-κB

BACKGROUND: This study examined the effects of gabexate mesilate on spinal nerve ligation (SNL)-induced neuropathic pain. To confirm the involvement of gabexate mesilate on neuroinflammation, we focused on the activation of nuclear factor-κB (NF-κB) and consequent the expression of proinflammatory c...

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Detalles Bibliográficos
Autores principales: Oh, Seon Hee, Lee, Hyun Young, Ki, Young Joon, Kim, Sang Hun, Lim, Kyung Joon, Jung, Ki Tae
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Pain Society 2020
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6944363/
https://www.ncbi.nlm.nih.gov/pubmed/31888315
http://dx.doi.org/10.3344/kjp.2020.33.1.30

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6944363/
https://www.ncbi.nlm.nih.gov/pubmed/31888315
http://dx.doi.org/10.3344/kjp.2020.33.1.30

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