Efficacy of a mitochondrion-targeting agent for reducing the level of urinary protein in rats with puromycin aminonucleoside-induced minimal-change nephrotic syndrome

BACKGROUND: Oxidative stress is a major factor responsible for minimal-change nephrotic syndrome (MCNS), which occurs most commonly in children. However, the influence of oxidative stress localized to mitochondria remains unclear. We examined the effect of a mitochondrion-targeting antioxidant, Mito...

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Detalles Bibliográficos
Autores principales: Fujii, Yuko, Matsumura, Hideki, Yamazaki, Satoshi, Shirasu, Akihiko, Nakakura, Hyogo, Ogihara, Tohru, Ashida, Akira
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6944386/
https://www.ncbi.nlm.nih.gov/pubmed/31905213
http://dx.doi.org/10.1371/journal.pone.0227414

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