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GC content shapes mRNA storage and decay in human cells

mRNA translation and decay appear often intimately linked although the rules of this interplay are poorly understood. In this study, we combined our recent P-body transcriptome with transcriptomes obtained following silencing of broadly acting mRNA decay and repression factors, and with available CL...

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Detalles Bibliográficos
Autores principales: Courel, Maïté, Clément, Yves, Bossevain, Clémentine, Foretek, Dominika, Vidal Cruchez, Olivia, Yi, Zhou, Bénard, Marianne, Benassy, Marie-Noëlle, Kress, Michel, Vindry, Caroline, Ernoult-Lange, Michèle, Antoniewski, Christophe, Morillon, Antonin, Brest, Patrick, Hubstenberger, Arnaud, Roest Crollius, Hugues, Standart, Nancy, Weil, Dominique
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6944446/
https://www.ncbi.nlm.nih.gov/pubmed/31855182
http://dx.doi.org/10.7554/eLife.49708