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Targeting the non-canonical roles of PCNA modifies and increases the response to targeted anti-cancer therapy
Receptor tyrosine kinases (RTKs), such as HER2 and/or EGFR are important therapeutic targets in multiple cancer cells. Low and/or short response to targeted therapies are often due to activation of compensatory signaling pathways, and therefore a combination of kinase inhibitors with other anti-canc...
Autores principales: | Søgaard, Caroline K., Nepal, Anala, Petrovic, Voin, Sharma, Animesh, Liabakk, Nina-Beate, Steigedal, Tonje S., Otterlei, Marit |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6944453/ https://www.ncbi.nlm.nih.gov/pubmed/31921382 http://dx.doi.org/10.18632/oncotarget.27267 |
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