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Activation of Distinct Channelrhodopsin Variants Engages Different Patterns of Network Activity

Several recently developed Channelrhodopsin (ChR) variants are characterized by rapid kinetics and reduced desensitization in comparison to the widely used ChR2. However, little is known about how varying opsin properties may regulate their interaction with local network dynamics. We compared evoked...

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Detalles Bibliográficos
Autores principales: Jun, Na Young, Cardin, Jessica A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society for Neuroscience 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6944482/
https://www.ncbi.nlm.nih.gov/pubmed/31822522
http://dx.doi.org/10.1523/ENEURO.0222-18.2019