Bone Health in Men with Prostate Cancer: Review Article

PURPOSE OF REVIEW: The improvement in prostate cancer survival over time, even in those with advanced disease, has led to an increasing recognition of the impact of prostate cancer and its treatment on bone health. Cancer treatment–induced bone loss (CTIBL) is a well-recognized entity but greater aw...

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Autores principales: A M El Badri, Salma, Salawu, Abdulazeez, Brown, Janet E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2019
Materias:
Cancer-induced Musculoskeletal Diseases (E Keller and J Sterling, Section Editors)
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6944652/
https://www.ncbi.nlm.nih.gov/pubmed/31760582
http://dx.doi.org/10.1007/s11914-019-00536-8
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author A M El Badri, Salma
Salawu, Abdulazeez
Brown, Janet E
author_facet A M El Badri, Salma
Salawu, Abdulazeez
Brown, Janet E
author_sort A M El Badri, Salma
collection PubMed
description PURPOSE OF REVIEW: The improvement in prostate cancer survival over time, even in those with advanced disease, has led to an increasing recognition of the impact of prostate cancer and its treatment on bone health. Cancer treatment–induced bone loss (CTIBL) is a well-recognized entity but greater awareness of the risks associated with CTIBL and its treatment is required. RECENT FINDINGS: The principal culprit in causing CTIBL is hormonal ablation induced by prostate cancer treatment, including several new agents which have been developed in recent years which significantly improve survival, but may cause CTIBL. This review discusses the impact of prostate cancer and its treatment on bone health, including published evidence on the underlying pathophysiology, assessment of bone health, and strategies for prevention and treatment. SUMMARY: It is important to recognize the potential cumulative impact of systemic prostate cancer treatments on bone health.
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spelling pubmed-69446522020-01-21 Bone Health in Men with Prostate Cancer: Review Article A M El Badri, Salma Salawu, Abdulazeez Brown, Janet E Curr Osteoporos Rep Cancer-induced Musculoskeletal Diseases (E Keller and J Sterling, Section Editors) PURPOSE OF REVIEW: The improvement in prostate cancer survival over time, even in those with advanced disease, has led to an increasing recognition of the impact of prostate cancer and its treatment on bone health. Cancer treatment–induced bone loss (CTIBL) is a well-recognized entity but greater awareness of the risks associated with CTIBL and its treatment is required. RECENT FINDINGS: The principal culprit in causing CTIBL is hormonal ablation induced by prostate cancer treatment, including several new agents which have been developed in recent years which significantly improve survival, but may cause CTIBL. This review discusses the impact of prostate cancer and its treatment on bone health, including published evidence on the underlying pathophysiology, assessment of bone health, and strategies for prevention and treatment. SUMMARY: It is important to recognize the potential cumulative impact of systemic prostate cancer treatments on bone health. Springer US 2019-11-23 2019 /pmc/articles/PMC6944652/ /pubmed/31760582 http://dx.doi.org/10.1007/s11914-019-00536-8 Text en © The Author(s) 2019 Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.
spellingShingle Cancer-induced Musculoskeletal Diseases (E Keller and J Sterling, Section Editors)
A M El Badri, Salma
Salawu, Abdulazeez
Brown, Janet E
Bone Health in Men with Prostate Cancer: Review Article
title Bone Health in Men with Prostate Cancer: Review Article
title_full Bone Health in Men with Prostate Cancer: Review Article
title_fullStr Bone Health in Men with Prostate Cancer: Review Article
title_full_unstemmed Bone Health in Men with Prostate Cancer: Review Article
title_short Bone Health in Men with Prostate Cancer: Review Article
title_sort bone health in men with prostate cancer: review article
topic Cancer-induced Musculoskeletal Diseases (E Keller and J Sterling, Section Editors)
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6944652/
https://www.ncbi.nlm.nih.gov/pubmed/31760582
http://dx.doi.org/10.1007/s11914-019-00536-8
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AT salawuabdulazeez bonehealthinmenwithprostatecancerreviewarticle
AT brownjanete bonehealthinmenwithprostatecancerreviewarticle

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