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The spatial binding model of the pioneer factor Oct4 with its target genes during cell reprogramming
Understanding the target regulation between pioneer factor and its binding genes is crucial for improving the efficiency of TF-mediated reprogramming. Oct4 as the only one factor that cannot be substituted by other POU members, it is urgent need to develop a quantitative model for describing the spa...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Research Network of Computational and Structural Biotechnology
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6944736/ https://www.ncbi.nlm.nih.gov/pubmed/31921389 http://dx.doi.org/10.1016/j.csbj.2019.09.002 |