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Nonsynonymous Mutations in Linker-2 of the Pdr5 Multidrug Transporter Identify a New RNA Stability Element

Analysis of synonymous mutations established that although the primary amino acid sequence remains unchanged, alterations in transcription and translation can result in significant phenotypic consequences. We report the novel observation that a series of nonsynonymous mutations in an unconserved str...

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Detalles Bibliográficos
Autores principales: Rahman, Hadiar, Rudrow, Andrew, Carneglia, Joshua, Joly, Sister Stephen Patrick, Nicotera, Dante, Naldrett, Michael, Choy, John, Ambudkar, Suresh V., Golin, John
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Genetics Society of America 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6945031/
https://www.ncbi.nlm.nih.gov/pubmed/31757931
http://dx.doi.org/10.1534/g3.119.400863