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Analysis of the audiological characteristics and comorbidity in patients with chronic tinnitus

Tinnitus is defined as perception of a sound without sound stimulation. This study aims to investigate the correlation between chronic tinnitus and the most significant clinical comorbidities and pharmacological treatments. We recruited 130 consecutive outpatients with a tinnitus for least from thre...

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Autores principales: Pavaci, Silva, Tortorella, Federica, Fioretti, Alessandra Barbara, Angelone, Anna Maria, Businco, Lino Di Rienzo, Lauriello, Maria, Eibenstein, Alberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PAGEPress Publications, Pavia, Italy 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6945072/
https://www.ncbi.nlm.nih.gov/pubmed/31929867
http://dx.doi.org/10.4081/audiores.2019.231
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author Pavaci, Silva
Tortorella, Federica
Fioretti, Alessandra Barbara
Angelone, Anna Maria
Businco, Lino Di Rienzo
Lauriello, Maria
Eibenstein, Alberto
author_facet Pavaci, Silva
Tortorella, Federica
Fioretti, Alessandra Barbara
Angelone, Anna Maria
Businco, Lino Di Rienzo
Lauriello, Maria
Eibenstein, Alberto
author_sort Pavaci, Silva
collection PubMed
description Tinnitus is defined as perception of a sound without sound stimulation. This study aims to investigate the correlation between chronic tinnitus and the most significant clinical comorbidities and pharmacological treatments. We recruited 130 consecutive outpatients with a tinnitus for least from three months and 100 subjects without tinnitus. All patients had a full medical and audiological evaluation and all filled in Tinnitus Handicap Inventory questionnaire and Khalfa’s Hyperacusis questionnaire. We also analyzed the qualitative variables: audiometry exam, tinnitus characteristics and psychometric questionnaires. Univariate logistic regression was performed to evaluate the associations between the presence of tinnitus and the presence of comorbidities and drug intake. The statistical analysis provided the following results in the group of patients with tinnitus. We obtained an Odds Ratio statistically significant for the following categories taken into consideration: the presence of anxiety and depression, neurological diseases, headache, temporomandibular joint (TMJ) disorders, intake of levothyroxine and proton-pump inhibitor. In this study, we tried to evaluate the audiological characteristics in the subjects affected by chronic tinnitus in order to find a possible correlation with the comorbidities and any drugs intake. We found a statistically significant correlation between tinnitus and comorbidities like anxiety, depression, TMJ disorders, dysthyroidism, headache and levothyroxine and PPI intake.
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spelling pubmed-69450722020-01-10 Analysis of the audiological characteristics and comorbidity in patients with chronic tinnitus Pavaci, Silva Tortorella, Federica Fioretti, Alessandra Barbara Angelone, Anna Maria Businco, Lino Di Rienzo Lauriello, Maria Eibenstein, Alberto Audiol Res Article Tinnitus is defined as perception of a sound without sound stimulation. This study aims to investigate the correlation between chronic tinnitus and the most significant clinical comorbidities and pharmacological treatments. We recruited 130 consecutive outpatients with a tinnitus for least from three months and 100 subjects without tinnitus. All patients had a full medical and audiological evaluation and all filled in Tinnitus Handicap Inventory questionnaire and Khalfa’s Hyperacusis questionnaire. We also analyzed the qualitative variables: audiometry exam, tinnitus characteristics and psychometric questionnaires. Univariate logistic regression was performed to evaluate the associations between the presence of tinnitus and the presence of comorbidities and drug intake. The statistical analysis provided the following results in the group of patients with tinnitus. We obtained an Odds Ratio statistically significant for the following categories taken into consideration: the presence of anxiety and depression, neurological diseases, headache, temporomandibular joint (TMJ) disorders, intake of levothyroxine and proton-pump inhibitor. In this study, we tried to evaluate the audiological characteristics in the subjects affected by chronic tinnitus in order to find a possible correlation with the comorbidities and any drugs intake. We found a statistically significant correlation between tinnitus and comorbidities like anxiety, depression, TMJ disorders, dysthyroidism, headache and levothyroxine and PPI intake. PAGEPress Publications, Pavia, Italy 2019-12-19 /pmc/articles/PMC6945072/ /pubmed/31929867 http://dx.doi.org/10.4081/audiores.2019.231 Text en ©Copyright: the Author(s), 2019 http://creativecommons.org/licenses/by-nc/4.0/ This article is distributed under the terms of the Creative Commons Attribution Noncommercial License (by-nc 4.0) which permits any noncommercial use, distribution, and reproduction in any medium, provided the original author(s) and source are credited.
spellingShingle Article
Pavaci, Silva
Tortorella, Federica
Fioretti, Alessandra Barbara
Angelone, Anna Maria
Businco, Lino Di Rienzo
Lauriello, Maria
Eibenstein, Alberto
Analysis of the audiological characteristics and comorbidity in patients with chronic tinnitus
title Analysis of the audiological characteristics and comorbidity in patients with chronic tinnitus
title_full Analysis of the audiological characteristics and comorbidity in patients with chronic tinnitus
title_fullStr Analysis of the audiological characteristics and comorbidity in patients with chronic tinnitus
title_full_unstemmed Analysis of the audiological characteristics and comorbidity in patients with chronic tinnitus
title_short Analysis of the audiological characteristics and comorbidity in patients with chronic tinnitus
title_sort analysis of the audiological characteristics and comorbidity in patients with chronic tinnitus
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6945072/
https://www.ncbi.nlm.nih.gov/pubmed/31929867
http://dx.doi.org/10.4081/audiores.2019.231
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