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Uncoupling protein 1 inhibits mitochondrial reactive oxygen species generation and alleviates acute kidney injury

BACKGROUND: Uncoupling protein 1 (UCP1) is predominantly found in brown adipose tissue mitochondria, and mediates energy dissipation to generate heat rather than ATP via functional mitochondrial uncoupling. However, little is known about its expression and function in kidney. METHODS: We carried out...

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Detalles Bibliográficos
Autores principales: Jia, Ping, Wu, Xiaoli, Pan, Tianyi, Xu, Sujuan, Hu, Jiachang, Ding, Xiaoqiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6945195/
https://www.ncbi.nlm.nih.gov/pubmed/31678001
http://dx.doi.org/10.1016/j.ebiom.2019.10.023