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Uncoupling protein 1 inhibits mitochondrial reactive oxygen species generation and alleviates acute kidney injury
BACKGROUND: Uncoupling protein 1 (UCP1) is predominantly found in brown adipose tissue mitochondria, and mediates energy dissipation to generate heat rather than ATP via functional mitochondrial uncoupling. However, little is known about its expression and function in kidney. METHODS: We carried out...
Autores principales: | Jia, Ping, Wu, Xiaoli, Pan, Tianyi, Xu, Sujuan, Hu, Jiachang, Ding, Xiaoqiang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6945195/ https://www.ncbi.nlm.nih.gov/pubmed/31678001 http://dx.doi.org/10.1016/j.ebiom.2019.10.023 |
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