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A novel strategy to block mitotic progression for targeted therapy

BACKGROUND: Blockade of mitotic progression is an ideal approach to induce mitotic catastrophe that suppresses cancer cell expansion. Cdc20 is a critical mitotic factor governing anaphase initiation and the exit from mitosis through recruiting substrates to APC/C for degradation. Results from recent...

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Detalles Bibliográficos
Autores principales:	Chi, Junlong (Jack), Li, Hongchun, Zhou, Zhuan, Izquierdo-Ferrer, Javier, Xue, Yifan, Wavelet, Cindy M., Schiltz, Gary E., Zhang, Bin, Cristofanilli, Massimo, Lu, Xinghua, Bahar, Ivet, Wan, Yong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2019
Materias:	Research paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6945239/ https://www.ncbi.nlm.nih.gov/pubmed/31669221 http://dx.doi.org/10.1016/j.ebiom.2019.10.013

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