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Tumor cells hijack enteric glia to activate colon cancer stem cells and stimulate tumorigenesis

BACKGROUND: Colon cancer stem cells (CSCs), considered responsible for tumor initiation and cancer relapse, are constantly exposed to regulatory cues emanating from neighboring cells present in the tumor microenvironment. Among these cells are enteric glial cells (EGCs) that are potent regulators of...

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Detalles Bibliográficos
Autores principales: Valès, Simon, Bacola, Gregory, Biraud, Mandy, Touvron, Mélissa, Bessard, Anne, Geraldo, Fanny, Dougherty, Kelsie A., Lashani, Shaian, Bossard, Céline, Flamant, Mathurin, Duchalais, Emilie, Marionneau-Lambot, Séverine, Oullier, Thibauld, Oliver, Lisa, Neunlist, Michel, Vallette, François M., Van Landeghem, Laurianne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6945247/
https://www.ncbi.nlm.nih.gov/pubmed/31662289
http://dx.doi.org/10.1016/j.ebiom.2019.09.045