Software development for hepatopulmonary shunt estimation by gamma camera method in transarterial radioembolization

Trans-arterial radioembolization (TARE) is an established treatment for inoperable hepatocellular carcinoma and liver metastases from Carcinoma of gastrointestinal tract. Radiation-induced toxicity to the lung parenchyma is the dose-limiting factor in TARE. Pretreatment hepatopulmonary shunt (HPS) i...

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Detalles Bibliográficos
Autores principales: Jha, Ashish Kumar, Mithun, Sneha, Puranik, Ameya, Purandare, Nilendu C., Shah, Sneha, Agrawal, Archi, Kulkarni, Suyash S., Shetty, Nitin, Rangarajan, Venkatesh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2019
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6945361/
https://www.ncbi.nlm.nih.gov/pubmed/31933552
http://dx.doi.org/10.4103/wjnm.WJNM_115_18
Descripción
Sumario:Trans-arterial radioembolization (TARE) is an established treatment for inoperable hepatocellular carcinoma and liver metastases from Carcinoma of gastrointestinal tract. Radiation-induced toxicity to the lung parenchyma is the dose-limiting factor in TARE. Pretreatment hepatopulmonary shunt (HPS) is estimated by gamma camera method by transarterial administration of 370MBq (99m)Tc macro aggregated albumin. We have developed HPS software on XELERIS-1.123 workstation, GE medical systems, Milwaukee, USA, for accurate calculation of HPS. This software has also been tested on a higher version of XELERIS workstation, and it has been found to work well in all versions.

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