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Ras isoforms: signaling specificities in CD40 pathway

BACKGROUND: Ras are small cellular GTPases which regulate diverse cellular processes. It has three isoforms: H-Ras, K-Ras, and N-Ras. Owing to the N-terminus (1–165 residues) sequence homology these isoforms were thought to be functionally redundant. However, only K-Ras-deficient mice but not H-Ras-...

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Detalles Bibliográficos
Autores principales: Nair, Arathi, Chakraborty, Sushmita, Banerji, Late Anirban, Srivastava, Ankita, Navare, Charudutta, Saha, Bhaskar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6945409/
https://www.ncbi.nlm.nih.gov/pubmed/31906952
http://dx.doi.org/10.1186/s12964-019-0497-1