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Safety, tolerability, and pharmacokinetics of repeated oral doses of 2-hydroxybenzylamine acetate in healthy volunteers: a double-blind, randomized, placebo-controlled clinical trial
BACKGROUND: 2-Hydroxybenzylamine (2-HOBA) is a selective dicarbonyl electrophile scavenger being developed as a nutritional supplement to help protect against the development of conditions associated with dicarbonyl electrophile formation, such as the cognitive decline observed with Mild Cognitive I...
Autores principales: | Pitchford, Lisa M., Driver, Patricia M., Fuller, John C., Akers, Wendell S., Abumrad, Naji N., Amarnath, Venkataraman, Milne, Ginger L., Chen, Sheau-Chiann, Ye, Fei, Roberts, L. Jackson, Shoemaker, M. Benjamin, Oates, John A., Rathmacher, John A., Boutaud, Olivier |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6945443/ https://www.ncbi.nlm.nih.gov/pubmed/31907026 http://dx.doi.org/10.1186/s40360-020-0382-y |
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