Genome-wide analysis reveals the association between alternative splicing and DNA methylation across human solid tumors

BACKGROUND: Dysregulation of alternative splicing (AS) is a critical signature of cancer. However, the regulatory mechanisms of cancer-specific AS events, especially the impact of DNA methylation, are poorly understood. METHODS: By using The Cancer Genome Atlas (TCGA) SpliceSeq and TCGA data for ten...

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Detalles Bibliográficos
Autores principales: Sun, Xiaohui, Tian, Yiping, Wang, Jianming, Sun, Zeyuan, Zhu, Yimin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6945449/
https://www.ncbi.nlm.nih.gov/pubmed/31906954
http://dx.doi.org/10.1186/s12920-019-0654-9

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