Loss of the SWI/SNF-ATPase subunit members SMARCF1 (ARID1A), SMARCA2 (BRM), SMARCA4 (BRG1) and SMARCB1 (INI1) in oesophageal adenocarcinoma

BACKGROUND: The SWI/SNF complex is an important chromatin remodeler, commonly dysregulated in cancer, with an estimated mutation frequency of 20%. ARID1A is the most frequently mutated subunit gene. Almost nothing is known about the other familiar members of the SWI/SNF complexes, SMARCA2 (BRM), SMA...

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Detalles Bibliográficos
Autores principales: Schallenberg, Simon, Bork, Julian, Essakly, Ahlem, Alakus, Hakan, Buettner, Reinhard, Hillmer, Axel M., Bruns, Christiane, Schroeder, Wolfgang, Zander, Thomas, Loeser, Heike, Gebauer, Florian, Quaas, Alexander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6945480/
https://www.ncbi.nlm.nih.gov/pubmed/31906887
http://dx.doi.org/10.1186/s12885-019-6425-3

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