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Prescreening for European Prevention of Alzheimer Dementia (EPAD) trial-ready cohort: impact of AD risk factors and recruitment settings

BACKGROUND: Recruitment is often a bottleneck in secondary prevention trials in Alzheimer disease (AD). Furthermore, screen-failure rates in these trials are typically high due to relatively low prevalence of AD pathology in individuals without dementia, especially among cognitively unimpaired. Pres...

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Detalles Bibliográficos
Autores principales: Vermunt, Lisa, Muniz-Terrera, Graciela, ter Meulen, Lea, Veal, Colin, Blennow, Kaj, Campbell, Archie, Carrié, Isabelle, Delrieu, Julien, Fauria, Karine, Huesa Rodríguez, Gema, Ingala, Silvia, Jenkins, Natalie, Molinuevo, José Luis, Ousset, Pierre-Jean, Porteous, David, Prins, Niels D., Solomon, Alina, Tom, Brian D., Zetterberg, Henrik, Zwan, Marissa, Ritchie, Craig W., Scheltens, Philip, Luscan, Gerald, Brookes, Anthony J., Visser, Pieter Jelle
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6945608/
https://www.ncbi.nlm.nih.gov/pubmed/31907067
http://dx.doi.org/10.1186/s13195-019-0576-y