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High levels of dietary methionine improves sitagliptin-induced hepatotoxicity by attenuating oxidative stress in hypercholesterolemic rats

BACKGROUND: Both cholesterol (Cho) and methionine (Met, a precursor for homocysteine) are risk factors for fatty liver disease. Since Western diets are rich in Cho and Met, we investigated the hepatic effects of feeding a diet enriched in Met and Cho. Further, based on the reported anti-oxidative an...

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Detalles Bibliográficos
Autores principales: Kumar, Avinash, Pathak, Rashmi, Palfrey, Henry A., Stone, Kirsten P., Gettys, Thomas W., Murthy, Subramanyam N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6945706/
https://www.ncbi.nlm.nih.gov/pubmed/31921324
http://dx.doi.org/10.1186/s12986-019-0422-z

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