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High levels of dietary methionine improves sitagliptin-induced hepatotoxicity by attenuating oxidative stress in hypercholesterolemic rats
BACKGROUND: Both cholesterol (Cho) and methionine (Met, a precursor for homocysteine) are risk factors for fatty liver disease. Since Western diets are rich in Cho and Met, we investigated the hepatic effects of feeding a diet enriched in Met and Cho. Further, based on the reported anti-oxidative an...
Autores principales: | Kumar, Avinash, Pathak, Rashmi, Palfrey, Henry A., Stone, Kirsten P., Gettys, Thomas W., Murthy, Subramanyam N. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6945706/ https://www.ncbi.nlm.nih.gov/pubmed/31921324 http://dx.doi.org/10.1186/s12986-019-0422-z |
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