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Lipid droplets in granulosa cells are correlated with reduced pregnancy rates

BACKGROUND: Lipids are an important source for energy production during oocyte maturation. The accumulation of intracellular lipids binds to proteins to form lipid droplets. This may lead to cellular lipotoxicity. The impact of lipotoxicity on cumulus and granulosa cells has been reported. This pilo...

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Detalles Bibliográficos
Autores principales: Raviv, Shira, Hantisteanu, Shay, Sharon, Shilhav Meisel, Atzmon, Yuval, Michaeli, Mediea, Shalom-Paz, Einat
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6945749/
https://www.ncbi.nlm.nih.gov/pubmed/31907049
http://dx.doi.org/10.1186/s13048-019-0606-1

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