Cargando…

Evolution of the SRGAP2 Gene Is Linked to Intelligence in Mammals

BACKGROUND/AIMS: A recent duplication of the gene encoding SLIT-ROBO Rho GTPase-activating protein 2 (SRGAP2) in the primate lineage has been proposed to be associated with the human-specific extraordinary development of intelligence. There is no report regarding the role of the SRGAP2 gene in the e...

Descripción completa

Detalles Bibliográficos
Autor principal:	Tiwary, Basant K.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	S. Karger AG 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6945801/ https://www.ncbi.nlm.nih.gov/pubmed/31988884 http://dx.doi.org/10.1159/000443947

Ejemplares similares

The human-specific paralogs SRGAP2B and SRGAP2C differentially modulate SRGAP2A-dependent synaptic development
por: Schmidt, Ewoud R. E., et al.
Publicado: (2019)

Structural History of Human SRGAP2 Proteins
por: Sporny, Michael, et al.
Publicado: (2017)

C5 and SRGAP3 Polymorphisms Are Linked to Paediatric Allergic Asthma in the Italian Population
por: Messelodi, Daria, et al.
Publicado: (2022)

Impact of klotho on the expression of SRGAP2a in podocytes in diabetic nephropathy
por: Jin, Donghua, et al.
Publicado: (2022)

Srgap2 suppression ameliorates retinal ganglion cell degeneration in mice
por: Gan, Yi-Jing, et al.
Publicado: (2023)

The Inverse F-BAR Domain Protein srGAP2 Acts through srGAP3 to Modulate Neuronal Differentiation and Neurite Outgrowth of Mouse Neuroblastoma Cells
por: Ma, Yue, et al.
Publicado: (2013)

The SRGAP2 SNPs, their haplotypes and G × E interactions on serum lipid traits
por: Miao, Liu, et al.
Publicado: (2017)

SRGAP2a: A New Player That Modulates Podocyte Cytoskeleton and Injury in Diabetes
por: Levi, Moshe, et al.
Publicado: (2018)

srGAP1 mediates the migration inhibition effect of Slit2-Robo1 in colorectal cancer
por: Feng, Yuyang, et al.
Publicado: (2016)

Evolution of trappin genes in mammals
por: Kato, Akira, et al.
Publicado: (2010)

srGAP2 deactivates RhoA to control the duration of thrombin-mediated endothelial permeability
por: Lopez Rioja, Alba, et al.
Publicado: (2022)

A Novel Microduplication in the Neurodevelopmental Gene SRGAP3 That Segregates with Psychotic Illness in the Family of a COS Proband
por: Wilson, Nicole K. A., et al.
Publicado: (2011)

Tyrosine dephosphorylated cortactin downregulates contractility at the epithelial zonula adherens through SRGAP1
por: Liang, Xuan, et al.
Publicado: (2017)

Diversification and the rate of molecular evolution: no evidence of a link in mammals
por: Goldie, Xavier, et al.
Publicado: (2011)

Stiff matrix induced srGAP2 tension gradients control migration direction in triple-negative breast cancer
por: Li, Chen, et al.
Publicado: (2023)

Tumor-Derived Exosomal miR-29b Reduces Angiogenesis in Pancreatic Cancer by Silencing ROBO1 and SRGAP2
por: Wang, Lihua, et al.
Publicado: (2022)

Dynamic expression of srGAP2 in cell nuclei and cytoplasm during the differentiation of rat neural stem cells in vitro
por: Jiao, Qian, et al.
Publicado: (2016)

A proliferative to invasive switch is mediated by srGAP1 downregulation through the activation of TGF-β2 signaling
por: Mondal, Chandrani, et al.
Publicado: (2022)

srGAP1 regulates lamellipodial dynamics and cell migratory behavior by modulating Rac1 activity
por: Yamazaki, Daisuke, et al.
Publicado: (2013)

Positive Selection and the Evolution of izumo Genes in Mammals
por: Grayson, Phil, et al.
Publicado: (2012)

Author Correction: Tyrosine dephosphorylated cortactin downregulates contractility at the epithelial zonula adherens through SRGAP1
por: Liang, Xuan, et al.
Publicado: (2017)

Evidence for a Role of srGAP3 in the Positioning of Commissural Axons within the Ventrolateral Funiculus of the Mouse Spinal Cord
por: Bacon, Claire, et al.
Publicado: (2011)

Electroacupuncture inhibits dendritic spine remodeling through the srGAP3-Rac1 signaling pathway in rats with SNL
por: Wu, Qiaoyun, et al.
Publicado: (2023)

Molecular Evolution of the TET Gene Family in Mammals
por: Akahori, Hiromichi, et al.
Publicado: (2015)

The Corticofugal Neuron-Associated Genes ROBO1, SRGAP1, and CTIP2 Exhibit an Anterior to Posterior Gradient of Expression in Early Fetal Human Neocortex Development
por: Ip, Bui Kar, et al.
Publicado: (2011)

Non-catalytic roles for TET1 protein negatively regulating neuronal differentiation through srGAP3 in neuroblastoma cells
por: Gao, Jie, et al.
Publicado: (2016)

The Evolution of Human Cancer Gene Duplications across Mammals
por: Tollis, Marc, et al.
Publicado: (2020)

Splicing and the Evolution of Proteins in Mammals
por: Parmley, Joanna L, et al.
Publicado: (2007)

SRGAP1, a crucial target of miR-340 and miR-124, functions as a potential oncogene in gastric tumorigenesis
por: Huang, Tingting, et al.
Publicado: (2017)

Microcephaly genes evolved adaptively throughout the evolution of eutherian mammals
por: Montgomery, Stephen H, et al.
Publicado: (2014)

Adaptive Evolution of Conserved Noncoding Elements in Mammals
por: Kim, Su Yeon, et al.
Publicado: (2007)

Complex intrachromosomal rearrangement in 1q leading to 1q32.2 microdeletion: a potential role of SRGAP2 in the gyrification of cerebral cortex
por: Rincic, Martina, et al.
Publicado: (2016)

Molecular Evolution of PTEN Pseudogenes in Mammals
por: Tang, Jingsi, et al.
Publicado: (2016)

Integrated network-based multiple computational analyses for identification of co-expressed candidate genes associated with neurological manifestations of COVID-19
por: Hazra, Suvojit, et al.
Publicado: (2022)

The role of heparan sulfate deficiency in autistic phenotype: potential involvement of Slit/Robo/srGAPs-mediated dendritic spine formation
por: Pérez, Christine, et al.
Publicado: (2016)

Genetic Signatures of Evolution of the Pluripotency Gene Regulating Network across Mammals
por: Endo, Yoshinori, et al.
Publicado: (2020)

Selective Pressures on Human Cancer Genes along the Evolution of Mammals
por: Vicens, Alberto, et al.
Publicado: (2018)

Genomic organization and adaptive evolution of IGHC genes in marine mammals
por: Li, Lili, et al.
Publicado: (2018)

Molecular evolution of the keratin associated protein gene family in mammals, role in the evolution of mammalian hair
por: Wu, Dong-Dong, et al.
Publicado: (2008)

SRGP-1/srGAP and AFD-1/afadin stabilize HMP-1/⍺-catenin at rosettes to seal internalization sites following gastrulation in C. elegans
por: Serre, Joel M., et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_s9tu9mgktvlkl1c7hnr25n5cku