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Pandrug-resistant Acinetobacter Baumannii Infection Identified in a Non-intensive Care Unit Patient: A Case Study

Acinetobacter baumannii is a major cause of hospital-acquired infections, particularly in patients treated in intensive care units (ICUs). It can be a causal agent of conditions like pneumonia, bacteremia, meningitis, soft-tissue, and urinary tract infections, and is associated with high mortality r...

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Autores principales: Balfousias, Theodore, Apostolopoulos, Alexandros, Angelis, Stavros, Filippou, Dimitrios, Maris, Spyridon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6946043/
https://www.ncbi.nlm.nih.gov/pubmed/31938612
http://dx.doi.org/10.7759/cureus.6321
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author Balfousias, Theodore
Apostolopoulos, Alexandros
Angelis, Stavros
Filippou, Dimitrios
Maris, Spyridon
author_facet Balfousias, Theodore
Apostolopoulos, Alexandros
Angelis, Stavros
Filippou, Dimitrios
Maris, Spyridon
author_sort Balfousias, Theodore
collection PubMed
description Acinetobacter baumannii is a major cause of hospital-acquired infections, particularly in patients treated in intensive care units (ICUs). It can be a causal agent of conditions like pneumonia, bacteremia, meningitis, soft-tissue, and urinary tract infections, and is associated with high mortality rates. We present a case of a 72-year-old male patient treated for fractured neck of femur who went on to develop an infection from a pandrug-resistant Acinetobacter baumannii isolated in blood and urine cultures during his hospitalization in trauma and orthopedic ward. The patient was operated on the second day following his injury with a cephalomedullary nail device and became febrile with rigors on day six. His clinical condition deteriorated over the next days and his inflammatory markers reached a peak value on day 10 post-injury. Acinetobacter baumannii was isolated from blood and urine cultures and a regimen combining rifampicin, tigecycline, and vancomycin in their maximum doses was initiated. The patient was discharged on day 26 post-injury. Before discharge, he had received the above-mentioned intravenous antibiotic regimen for 14 days. He had also been afebrile for six days and undergone three consecutive negative blood culture samples.
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spelling pubmed-69460432020-01-14 Pandrug-resistant Acinetobacter Baumannii Infection Identified in a Non-intensive Care Unit Patient: A Case Study Balfousias, Theodore Apostolopoulos, Alexandros Angelis, Stavros Filippou, Dimitrios Maris, Spyridon Cureus Orthopedics Acinetobacter baumannii is a major cause of hospital-acquired infections, particularly in patients treated in intensive care units (ICUs). It can be a causal agent of conditions like pneumonia, bacteremia, meningitis, soft-tissue, and urinary tract infections, and is associated with high mortality rates. We present a case of a 72-year-old male patient treated for fractured neck of femur who went on to develop an infection from a pandrug-resistant Acinetobacter baumannii isolated in blood and urine cultures during his hospitalization in trauma and orthopedic ward. The patient was operated on the second day following his injury with a cephalomedullary nail device and became febrile with rigors on day six. His clinical condition deteriorated over the next days and his inflammatory markers reached a peak value on day 10 post-injury. Acinetobacter baumannii was isolated from blood and urine cultures and a regimen combining rifampicin, tigecycline, and vancomycin in their maximum doses was initiated. The patient was discharged on day 26 post-injury. Before discharge, he had received the above-mentioned intravenous antibiotic regimen for 14 days. He had also been afebrile for six days and undergone three consecutive negative blood culture samples. Cureus 2019-12-07 /pmc/articles/PMC6946043/ /pubmed/31938612 http://dx.doi.org/10.7759/cureus.6321 Text en Copyright © 2019, Balfousias et al. http://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Orthopedics
Balfousias, Theodore
Apostolopoulos, Alexandros
Angelis, Stavros
Filippou, Dimitrios
Maris, Spyridon
Pandrug-resistant Acinetobacter Baumannii Infection Identified in a Non-intensive Care Unit Patient: A Case Study
title Pandrug-resistant Acinetobacter Baumannii Infection Identified in a Non-intensive Care Unit Patient: A Case Study
title_full Pandrug-resistant Acinetobacter Baumannii Infection Identified in a Non-intensive Care Unit Patient: A Case Study
title_fullStr Pandrug-resistant Acinetobacter Baumannii Infection Identified in a Non-intensive Care Unit Patient: A Case Study
title_full_unstemmed Pandrug-resistant Acinetobacter Baumannii Infection Identified in a Non-intensive Care Unit Patient: A Case Study
title_short Pandrug-resistant Acinetobacter Baumannii Infection Identified in a Non-intensive Care Unit Patient: A Case Study
title_sort pandrug-resistant acinetobacter baumannii infection identified in a non-intensive care unit patient: a case study
topic Orthopedics
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6946043/
https://www.ncbi.nlm.nih.gov/pubmed/31938612
http://dx.doi.org/10.7759/cureus.6321
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