Cargando…

The alternative cap-binding complex is required for antiviral defense in vivo

Cellular response to environmental challenges requires immediate and precise regulation of transcriptional programs. During viral infections, this includes the expression of antiviral genes that are essential to combat the pathogen. Transcribed mRNAs are bound and escorted to the cytoplasm by the ca...

Descripción completa

Detalles Bibliográficos
Autores principales:	Gebhardt, Anna, Bergant, Valter, Schnepf, Daniel, Moser, Markus, Meiler, Arno, Togbe, Dieudonnée, Mackowiak, Claire, Reinert, Line S., Paludan, Søren R., Ryffel, Bernhard, Stukalov, Alexey, Staeheli, Peter, Pichlmair, Andreas
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2019
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6946169/ https://www.ncbi.nlm.nih.gov/pubmed/31856218 http://dx.doi.org/10.1371/journal.ppat.1008155

Ejemplares similares

TREM2 is down-regulated by HSV1 in microglia and involved in antiviral defense in the brain
por: Fruhwürth, Stefanie, et al.
Publicado: (2023)

Effects of Nintedanib in an Animal Model of Liver Fibrosis
por: Wollin, Lutz, et al.
Publicado: (2020)

mRNA 3’UTR lengthening by alternative polyadenylation attenuates inflammatory responses and correlates with virulence of Influenza A virus
por: Bergant, Valter, et al.
Publicado: (2023)

Editorial: Ozone as a Driver of Lung Inflammation and Innate Immunity and as a Model for Lung Disease
por: Chung, Kian Fan, et al.
Publicado: (2021)

Influenza A Virus Infection Reactivates Human Endogenous Retroviruses Associated with Modulation of Antiviral Immunity
por: Liu, Hengyuan, et al.
Publicado: (2022)

STING is redundant for host defense and pathology of COVID-19-like disease in mice
por: Marino, Giorgia, et al.
Publicado: (2023)

mRNA export through an additional cap-binding complex consisting of NCBP1 and NCBP3
por: Gebhardt, Anna, et al.
Publicado: (2015)

Oxidative Stress in Ozone-Induced Chronic Lung Inflammation and Emphysema: A Facet of Chronic Obstructive Pulmonary Disease
por: Wiegman, Coen H., et al.
Publicado: (2020)

Experimental atopic dermatitis depends on IL-33R signaling via MyD88 in dendritic cells
por: Li, Changwei, et al.
Publicado: (2017)

Viral targeting of TFIIB impairs de novo polymerase II recruitment and affects antiviral immunity
por: Haas, Darya A., et al.
Publicado: (2018)

Acute Respiratory Barrier Disruption by Ozone Exposure in Mice
por: Sokolowska, Milena, et al.
Publicado: (2019)

STING agonists enable antiviral cross-talk between human cells and confer protection against genital herpes in mice
por: Skouboe, Morten K., et al.
Publicado: (2018)

Oxeiptosis – a ROS induced caspase-independent apoptosis-like cell death pathway
por: Holze, Cathleen, et al.
Publicado: (2017)

ILC3-derived acetylcholine promotes protease-driven allergic lung pathology
por: Darby, Matthew, et al.
Publicado: (2021)

Interleukin-17 is a negative regulator of established allergic asthma
por: Schnyder-Candrian, Silvia, et al.
Publicado: (2006)

Thymic Stromal Lymphopoietin Enhances Th2/Th22 and Reduces IL-17A in Protease-Allergen-Induced Airways Inflammation
por: Togbe, Dieudonnée, et al.
Publicado: (2013)

Attenuation of SARS‐CoV‐2 replication and associated inflammation by concomitant targeting of viral and host cap 2'‐O‐ribose methyltransferases
por: Bergant, Valter, et al.
Publicado: (2022)

Hippocampal interleukin-33 mediates neuroinflammation-induced cognitive impairments
por: Reverchon, Flora, et al.
Publicado: (2020)

STING agonist diABZI induces PANoptosis and DNA mediated acute respiratory distress syndrome (ARDS)
por: Messaoud-Nacer, Yasmine, et al.
Publicado: (2022)

Aryl hydrocarbon receptor (Ahr)‐dependent Il‐22 expression by type 3 innate lymphoid cells control of acute joint inflammation
por: Nehmar, Ramzi, et al.
Publicado: (2021)

Sensing of HSV-1 by the cGAS–STING pathway in microglia orchestrates antiviral defence in the CNS
por: Reinert, Line S., et al.
Publicado: (2016)

SS7-3 A non-redundant role of IFN-λ in antiviral defense of the intestinal tract
por: Mordstein, Markus, et al.
Publicado: (2010)

Potential Role of the Micro-Immunotherapy Medicine 2LALERG in the Treatment of Pollen-Induced Allergic Inflammation
por: Floris, Ilaria, et al.
Publicado: (2020)

Activation and Evasion of Innate Antiviral Immunity by Herpes Simplex Virus
por: Melchjorsen, Jesper, et al.
Publicado: (2009)

Antiviral Defense in Invertebrates
por: Flenniken, Michelle L.
Publicado: (2018)

Interferon-λ Contributes to Innate Immunity of Mice against Influenza A Virus but Not against Hepatotropic Viruses
por: Mordstein, Markus, et al.
Publicado: (2008)

Ozone-Induced Aryl Hydrocarbon Receptor Activation Controls Lung Inflammation via Interleukin-22 Modulation
por: Michaudel, Chloé, et al.
Publicado: (2020)

The Micro-Immunotherapy Medicine 2LEID Exhibits an Immunostimulant Effect by Boosting Both Innate and Adaptive Immune Responses
por: Jacques, Camille, et al.
Publicado: (2021)

Antiviral defense: interferons and beyond
por: Stetson, Daniel B., et al.
Publicado: (2006)

Evolution of viruses and antiviral defense
por: Moelling, Karin
Publicado: (2009)

Lipids in Innate Antiviral Defense
por: Schoggins, John W., et al.
Publicado: (2013)

Dendritic Cells and Antiviral Defense
por: Mailliard, Robbie B.
Publicado: (2020)

Role of IL-1β in Experimental Cystic Fibrosis upon P. aeruginosa Infection
por: Palomo, Jennifer, et al.
Publicado: (2014)

System-Based Approaches to Delineate the Antiviral Innate Immune Landscape
por: Krey, Karsten, et al.
Publicado: (2020)

The lysine methyltransferase SMYD3 interacts with hepatitis C virus NS5A and is a negative regulator of viral particle production
por: Eberle, Carol-Ann, et al.
Publicado: (2014)

RNAi and Antiviral Defense in the Honey Bee
por: Brutscher, Laura M., et al.
Publicado: (2015)

Cell senescence is an antiviral defense mechanism
por: Baz-Martínez, Maite, et al.
Publicado: (2016)

Rhabdoviruses, Antiviral Defense, and SUMO Pathway
por: El Asmi, Faten, et al.
Publicado: (2018)

SUMOylation in Viral Replication and Antiviral Defense
por: Fan, Yao, et al.
Publicado: (2022)

Adoptive Transfer of Induced-Treg Cells Effectively Attenuates Murine Airway Allergic Inflammation
por: Xu, Wei, et al.
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_astc2rc73422qttvegda6t2im1