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A good response to glucocorticoid for Henoch–Schönlein purpura with abdominal pain and gastrointestinal bleeding in an adult: A CARE case report

RATIONALE: Henoch–Schönlein purpura (HSP) is a small-vessel vasculitis that has been extensively studied in children, but little is known about its natural history in adults. There is no consensus regarding the treatment of glucocorticosteroids use for HSP. The efficacy of glucocorticoid for prevent...

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Autores principales: Yi, Fangfang, Bai, Zhaohui, Li, Yingying, Xu, Xiangbo, Guo, Xiaozhong, Qi, Xingshun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer Health 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6946351/
https://www.ncbi.nlm.nih.gov/pubmed/31895810
http://dx.doi.org/10.1097/MD.0000000000018602
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author Yi, Fangfang
Bai, Zhaohui
Li, Yingying
Xu, Xiangbo
Guo, Xiaozhong
Qi, Xingshun
author_facet Yi, Fangfang
Bai, Zhaohui
Li, Yingying
Xu, Xiangbo
Guo, Xiaozhong
Qi, Xingshun
author_sort Yi, Fangfang
collection PubMed
description RATIONALE: Henoch–Schönlein purpura (HSP) is a small-vessel vasculitis that has been extensively studied in children, but little is known about its natural history in adults. There is no consensus regarding the treatment of glucocorticosteroids use for HSP. The efficacy of glucocorticoid for preventing from severe complications or relapse is also controversial in HSP. PATIENT CONCERNS: A 21-year-old male was admitted to the hospital due to abdominal pain for more than 20 days, hematochezia for more than 10 days, and rash for 2 days. DIAGNOSES: The diagnosis of HSP is based on the European League against Rheumatism and the Paediatric Rheumatology European Society in 2006. INTERVENTIONS: The patient received glucocorticosteroids treatment for 17 days at the time of first hospitalization. OUTCOMES: The abdominal pain and hematochezia completely disappeared on the 6th day after the use of glucocorticosteroids, and purpura completely disappeared on the 8th day. LESSONS: Our patient has a good response to glucocorticoid. Glucocorticosteroids may be effective for the treatment of HSP.
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spelling pubmed-69463512020-01-31 A good response to glucocorticoid for Henoch–Schönlein purpura with abdominal pain and gastrointestinal bleeding in an adult: A CARE case report Yi, Fangfang Bai, Zhaohui Li, Yingying Xu, Xiangbo Guo, Xiaozhong Qi, Xingshun Medicine (Baltimore) 4200 RATIONALE: Henoch–Schönlein purpura (HSP) is a small-vessel vasculitis that has been extensively studied in children, but little is known about its natural history in adults. There is no consensus regarding the treatment of glucocorticosteroids use for HSP. The efficacy of glucocorticoid for preventing from severe complications or relapse is also controversial in HSP. PATIENT CONCERNS: A 21-year-old male was admitted to the hospital due to abdominal pain for more than 20 days, hematochezia for more than 10 days, and rash for 2 days. DIAGNOSES: The diagnosis of HSP is based on the European League against Rheumatism and the Paediatric Rheumatology European Society in 2006. INTERVENTIONS: The patient received glucocorticosteroids treatment for 17 days at the time of first hospitalization. OUTCOMES: The abdominal pain and hematochezia completely disappeared on the 6th day after the use of glucocorticosteroids, and purpura completely disappeared on the 8th day. LESSONS: Our patient has a good response to glucocorticoid. Glucocorticosteroids may be effective for the treatment of HSP. Wolters Kluwer Health 2020-01-03 /pmc/articles/PMC6946351/ /pubmed/31895810 http://dx.doi.org/10.1097/MD.0000000000018602 Text en Copyright © 2020 the Author(s). Published by Wolters Kluwer Health, Inc. http://creativecommons.org/licenses/by/4.0 This is an open access article distributed under the Creative Commons Attribution License 4.0 (CCBY), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. http://creativecommons.org/licenses/by/4.0
spellingShingle 4200
Yi, Fangfang
Bai, Zhaohui
Li, Yingying
Xu, Xiangbo
Guo, Xiaozhong
Qi, Xingshun
A good response to glucocorticoid for Henoch–Schönlein purpura with abdominal pain and gastrointestinal bleeding in an adult: A CARE case report
title A good response to glucocorticoid for Henoch–Schönlein purpura with abdominal pain and gastrointestinal bleeding in an adult: A CARE case report
title_full A good response to glucocorticoid for Henoch–Schönlein purpura with abdominal pain and gastrointestinal bleeding in an adult: A CARE case report
title_fullStr A good response to glucocorticoid for Henoch–Schönlein purpura with abdominal pain and gastrointestinal bleeding in an adult: A CARE case report
title_full_unstemmed A good response to glucocorticoid for Henoch–Schönlein purpura with abdominal pain and gastrointestinal bleeding in an adult: A CARE case report
title_short A good response to glucocorticoid for Henoch–Schönlein purpura with abdominal pain and gastrointestinal bleeding in an adult: A CARE case report
title_sort good response to glucocorticoid for henoch–schönlein purpura with abdominal pain and gastrointestinal bleeding in an adult: a care case report
topic 4200
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6946351/
https://www.ncbi.nlm.nih.gov/pubmed/31895810
http://dx.doi.org/10.1097/MD.0000000000018602
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