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APOE ε4, white matter hyperintensities, and cognition in Alzheimer and Lewy body dementia

OBJECTIVE: To determine if APOE ε4 influences the association between white matter hyperintensities (WMH) and cognitive impairment in Alzheimer disease (AD) and dementia with Lewy bodies (DLB). METHODS: A total of 289 patients (AD = 239; DLB = 50) underwent volumetric MRI, neuropsychological testing...

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Detalles Bibliográficos
Autores principales: Mirza, Saira Saeed, Saeed, Usman, Knight, Jo, Ramirez, Joel, Stuss, Donald T., Keith, Julia, Nestor, Sean M., Yu, Di, Swardfager, Walter, Rogaeva, Ekaterina, St. George Hyslop, Peter, Black, Sandra E., Masellis, Mario
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6946485/
https://www.ncbi.nlm.nih.gov/pubmed/31575706
http://dx.doi.org/10.1212/WNL.0000000000008377