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Applications of genome editing technology in the targeted therapy of human diseases: mechanisms, advances and prospects

Based on engineered or bacterial nucleases, the development of genome editing technologies has opened up the possibility of directly targeting and modifying genomic sequences in almost all eukaryotic cells. Genome editing has extended our ability to elucidate the contribution of genetics to disease...

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Detalles Bibliográficos
Autores principales: Li, Hongyi, Yang, Yang, Hong, Weiqi, Huang, Mengyuan, Wu, Min, Zhao, Xia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6946647/
https://www.ncbi.nlm.nih.gov/pubmed/32296011
http://dx.doi.org/10.1038/s41392-019-0089-y