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The neurobiology of treatment-resistant schizophrenia: paths to antipsychotic resistance and a roadmap for future research
Treatment-resistant schizophrenia (TRS), the persistence of positive symptoms despite ≥2 trials of adequate dose and duration of antipsychotic medication with documented adherence, is a serious clinical problem with heterogeneous presentations. TRS can vary in its onset (at the first episode of psyc...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6946650/ https://www.ncbi.nlm.nih.gov/pubmed/31911624 http://dx.doi.org/10.1038/s41537-019-0090-z |