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The neurobiology of treatment-resistant schizophrenia: paths to antipsychotic resistance and a roadmap for future research

Treatment-resistant schizophrenia (TRS), the persistence of positive symptoms despite ≥2 trials of adequate dose and duration of antipsychotic medication with documented adherence, is a serious clinical problem with heterogeneous presentations. TRS can vary in its onset (at the first episode of psyc...

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Detalles Bibliográficos
Autores principales: Potkin, Steven G., Kane, John M., Correll, Christoph U., Lindenmayer, Jean-Pierre, Agid, Ofer, Marder, Stephen R., Olfson, Mark, Howes, Oliver D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6946650/
https://www.ncbi.nlm.nih.gov/pubmed/31911624
http://dx.doi.org/10.1038/s41537-019-0090-z

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