TGF-β induces ST2 and programs ILC2 development

The molecular pathways underlying the development of innate lymphoid cells (ILCs) are mostly unknown. Here we show that TGF-β signaling programs the development of ILC2s from their progenitors. Specifically, the deficiency of TGF-β receptor II in bone marrow progenitors results in inefficient develo...

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Detalles Bibliográficos
Autores principales: Wang, Li, Tang, Jun, Yang, Xia, Zanvit, Peter, Cui, Kairong, Ku, Wai Lim, Jin, Wenwen, Zhang, Dunfang, Goldberg, Nathan, Cain, Alexander, Ni, Bing, Zhao, Keji, Wu, Yuzhang, Chen, WanJun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6946674/
https://www.ncbi.nlm.nih.gov/pubmed/31911623
http://dx.doi.org/10.1038/s41467-019-13734-w

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