Focal adhesion protein Kindlin-2 regulates bone homeostasis in mice

Our recent studies demonstrate that the focal adhesion protein Kindlin-2 is critical for chondrogenesis and early skeletal development. Here, we show that deleting Kindlin-2 from osteoblasts using the 2.3-kb mouse Col1a1-Cre transgene minimally impacts bone mass in mice, but deleting Kindlin-2 using...

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Detalles Bibliográficos
Autores principales: Cao, Huiling, Yan, Qinnan, Wang, Dong, Lai, Yumei, Zhou, Bo, Zhang, Qi, Jin, Wenfei, Lin, Simin, Lei, Yiming, Ma, Liting, Guo, Yuxi, Wang, Yishu, Wang, Yilin, Bai, Xiaochun, Liu, Chuanju, Feng, Jian Q., Wu, Chuanyue, Chen, Di, Cao, Xu, Xiao, Guozhi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6946678/
https://www.ncbi.nlm.nih.gov/pubmed/31934494
http://dx.doi.org/10.1038/s41413-019-0073-8

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