Transmission of tauopathy strains is independent of their isoform composition

The deposition of pathological tau is a common feature in several neurodegenerative tauopathies. Although equal ratios of tau isoforms with 3 (3R) and 4 (4R) microtubule-binding repeats are expressed in the adult human brain, the pathological tau from different tauopathies have distinct isoform comp...

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Detalles Bibliográficos
Autores principales: He, Zhuohao, McBride, Jennifer D., Xu, Hong, Changolkar, Lakshmi, Kim, Soo-jung, Zhang, Bin, Narasimhan, Sneha, Gibbons, Garrett S., Guo, Jing L., Kozak, Michael, Schellenberg, Gerard D., Trojanowski, John Q., Lee, Virginia M. -Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6946697/
https://www.ncbi.nlm.nih.gov/pubmed/31911587
http://dx.doi.org/10.1038/s41467-019-13787-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6946697/
https://www.ncbi.nlm.nih.gov/pubmed/31911587
http://dx.doi.org/10.1038/s41467-019-13787-x

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