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Plasma cathepsin D activity is negatively associated with hepatic insulin sensitivity in overweight and obese humans

AIMS/HYPOTHESIS: Insulin resistance in skeletal muscle and liver plays a major role in the pathophysiology of type 2 diabetes. The hyperinsulinaemic–euglycaemic clamp is considered the gold standard for assessing peripheral and hepatic insulin sensitivity, yet it is a costly and labour-intensive pro...

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Detalles Bibliográficos
Autores principales:	Ding, Lingling, Goossens, Gijs H., Oligschlaeger, Yvonne, Houben, Tom, Blaak, Ellen E., Shiri-Sverdlov, Ronit
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer Berlin Heidelberg 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6946744/ https://www.ncbi.nlm.nih.gov/pubmed/31690989 http://dx.doi.org/10.1007/s00125-019-05025-2

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