CARD9 Is Required for Classical Macrophage Activation and the Induction of Protective Immunity against Pulmonary Cryptococcosis

Caspase recruitment domain-containing protein 9 (CARD9) is a critical adaptor molecule triggered by the interaction of C-type lectin receptors (CLRs) with carbohydrate motifs found in fungi. Consequently, clinical and animal studies indicate that CARD9 is an important regulator of protective immunit...

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Detalles Bibliográficos
Autores principales: Campuzano, Althea, Castro-Lopez, Natalia, Martinez, Amanda J., Olszewski, Michal A., Ganguly, Anutosh, Leopold Wager, Chrissy, Hung, Chiung-Yu, Wormley, Floyd L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6946806/
https://www.ncbi.nlm.nih.gov/pubmed/31911495
http://dx.doi.org/10.1128/mBio.03005-19

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