Identification of osteoclast-osteoblast coupling factors in humans reveals links between bone and energy metabolism

Bone remodeling consists of resorption by osteoclasts followed by formation by osteoblasts, and osteoclasts are a source of bone formation-stimulating factors. Here we utilize osteoclast ablation by denosumab (DMAb) and RNA-sequencing of bone biopsies from postmenopausal women to identify osteoclast...

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Detalles Bibliográficos
Autores principales: Weivoda, Megan M., Chew, Chee Kian, Monroe, David G., Farr, Joshua N., Atkinson, Elizabeth J., Geske, Jennifer R., Eckhardt, Brittany, Thicke, Brianne, Ruan, Ming, Tweed, Amanda J., McCready, Louise K., Rizza, Robert A., Matveyenko, Aleksey, Kassem, Moustapha, Andersen, Thomas Levin, Vella, Adrian, Drake, Matthew T., Clarke, Bart L., Oursler, Merry Jo, Khosla, Sundeep
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6946812/
https://www.ncbi.nlm.nih.gov/pubmed/31911667
http://dx.doi.org/10.1038/s41467-019-14003-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6946812/
https://www.ncbi.nlm.nih.gov/pubmed/31911667
http://dx.doi.org/10.1038/s41467-019-14003-6

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