Frequency and Clinical Outcomes of CYP2C19 Genotype-Guided Escalation and De-escalation of Antiplatelet Therapy in a Real-World Clinical Setting

PURPOSE: To evaluate the frequency and clinical impact of switches in antiplatelet therapy following implementation of CYP2C19 genotyping after percutaneous coronary intervention (PCI). METHODS: The frequency of escalation (clopidogrel switched to prasugrel/ticagrelor) and de-escalation (prasugrel/t...

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Detalles Bibliográficos
Autores principales: Martin, Jesse, Williams, Alexis K., Klein, Melissa D., Sriramoju, Vindhya B., Madan, Shivanshu, Rossi, Joseph S., Clarke, Megan, Cicci, Jonathan D., Cavallari, Larisa H., Weck, Karen E., Stouffer, George A., Lee, Craig R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6946839/
https://www.ncbi.nlm.nih.gov/pubmed/31316169
http://dx.doi.org/10.1038/s41436-019-0611-1

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