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Endoplasmic Reticulum Stress Induces miR-706, A Pro-Cell Death microRNA, in A Protein Kinase RNA-Like ER Kinase (PERK) and Activating Transcription Factor 4 (ATF4) Dependent Manner

OBJECTIVE: Endoplasmic reticulum (ER) stress causes an adaptive response initiated by protein kinase RNA-like ER kinase (PERK), Ire1 and ATF6. It has been reported that these upstream regulators induce microRNAs. The current study was designed to find a novel microRNA that mediates ER stress compone...

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Detalles Bibliográficos
Autores principales: Wang, Xiu, Han, Yi, Hu, Guodong, Guo, Jianbo, Chen, Hongyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royan Institute 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6947010/
https://www.ncbi.nlm.nih.gov/pubmed/31863666
http://dx.doi.org/10.22074/cellj.2020.6873